in vitro evaluation of nickel oxide-based nanocomposite as wound dressing material against the bacterium isolated from burns
نویسندگان
چکیده
the introduction of newly devised wound dressing has been a major breakthrough in the management of wounds or infections. the aims of this paper are to isolate and identify bacterial species causing burn wound infections from a university-related iranian hospital as well as determination of the antimicrobial susceptibility of the isolated microorganisms to newly devised nanocomposite materials for developing efficient wound dressing. the nio nanoparticles were generated in situ and subsequently impregnated on the surface of cotton fabrics using ultrasound irradiation. then, surface modification was performed to reduce initial bacterial attachment using polyethylene glycol. cotton fabric was characterized by measuring scanning electron microscope (sem), x-ray diffraction (xrd) and antibacterial properties. disk diffusion method was used to quantify the efficacy of nio-based wound dressing against the most common burn wound pathogen, pseudomonas aeruginosa, isolated from burns and wound swabs patients of emam burn and accidents hospital in isfahan province, iran. all isolates showed high resistance to the commonly used antibiotic (ampicillin, gentamicin, cephalexin, co-trimoxazole and amoxicillin). in vitro evaluation showed that the modified cottons exhibited excellent biocidal action against high-resistant isolated gram-negative bacteria compared to unmodified ones. the results suggested that nio nanoparticles may be considered as an effective component of therapy for burn infections and in the combination with different antibacterial agents to overcome the resistance of the microorganisms and to obtain synergic antibacterial activity.
منابع مشابه
In vitro evaluation of nickel oxide-based nanocomposite as wound dressing material against the bacterium isolated from burns
The introduction of newly devised wound dressing has been a major breakthrough in the management of wounds or infections. The aims of this paper are to isolate and identify bacterial species causing burn wound infections from a University-related Iranian hospital as well as determination of the antimicrobial susceptibility of the isolated microorganisms to newly devised nanocomposite materials ...
متن کاملReduced Graphene Oxide-Cr2O3 Nanocomposite as Electrode Material in Supercapacitors
In recent years, electrochemical supercapacitors have received considerable attention from many researchers. Metal oxides such as chromium oxide with high redox activity, high specific capacity, and excellent reversibility are suitable alternatives to ruthenium oxide in supercapacitor applications. In this study, first, graphene oxide (GO) was synthesized by the modified Hummers method. The syn...
متن کاملPVA–clay nanocomposite hydrogels for wound dressing
Polymer gels as soft biomaterials have found diverse applications in biomedical field, e.g. in management and care of wound as wound dressing. The recent researches on nanocomposite materials have shown that some properties of polymers and gels significantly improve by adding organoclay into polymeric matrix. In this work, in order to obtain wound dressing with better properties, nanocomposite ...
متن کاملpreparation and evaluation of the chitosan composite films containing nitrofurazone as a burn wound dressing material
متن کامل
assessment of the effect of honey as a topical therapy for intra oral wound healing in rat.
چکیده ندارد.
15 صفحه اولSynthesis and evaluation of nanohydrogel film containing polyvinyl alcohol/hyaluronic acid/zinc oxide for wound dressing
Background and Aim: Lesions of the skin can impair its vital function to protect humans against external pathogens. Therefore, producing a suitable wound dressing to repair injuries is always one of the challenges of researchers. The present study aims to Synthesize a hydrogel film for wound dressing applications. Methods: In this research, a hydrogel film of polyvinyl alcohol / hyaluronic a...
متن کاملمنابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
international journal of molecular and clinical microbiologyجلد ۳، شماره ۱، صفحات ۲۶۶-۲۷۳
کلمات کلیدی
میزبانی شده توسط پلتفرم ابری doprax.com
copyright © 2015-2023